Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Adherence to all Good Manufacturing Practices (GMP) Safety Standards

Job Description

About the Role

The Small-Scale Purification Scientist is a hands-on technical contributor in the Bioprocess Design Center (BDC), responsible for designing, executing, and documenting downstream purification experiments that generate high-quality technical evidence for Thermo Fisher Scientific’s single-use purification technologies.

This role operates at the intersection of experimental execution and systems-level process understanding. The successful candidate will independently own small-scale downstream studies, translate experimental outcomes into actionable insights, and support integrated end-to-end workflow development across upstream, harvest, and downstream unit operations. Familiarity with Thermo Fisher Scientific’s single-use downstream purification equipment, consumables, and workflow architectures is highly valued and will enable rapid execution within BDC laboratory and customer-facing environments.

Key Responsibilities

Experimental Design & Execution

Execute purification resin design studies for internal and external customers using Thermo Fishers brand resins.Independently design and execute small-scale downstream purification experiments spanning capture, intermediate, and polishing operations.Develop experimental plans aligned to defined technical objectives, including appropriate controls, success criteria, and data quality expectations.Execute chromatography and filtration processes (e.g., column screening, process optimization, UF/DF) with a focus on Thermo Fisher single-use chromatography and centrifugation systems.Troubleshoot experimental issues and drive resolution with minimal supervision.

Systems & Workflow Awareness

Apply systems-level thinking to understand how downstream purification integrates with upstream processes, automation, analytics, and overall workflow design.Support evaluation of single-use purification technologies, process configurations, and operating strategies.Identify operational risks, constraints, and improvement opportunities during experimental execution.

Data Analysis & Documentation

Analyze experimental data, identify trends, and draw scientifically defensible conclusions.Author protocols, technical reports, summaries, and SOPs suitable for internal use and customer-facing communication.Maintain complete, accurate laboratory notebooks and records in accordance with internal data integrity and IP standards.

Collaboration & Communication

Support customer visits, technical demonstrations, and internal reviews by clearly articulating experimental intent, methods, and results.Communicate progress, risks, and outcomes effectively to both technical and non-technical stakeholders.

Laboratory Operations & Compliance

Maintain a safe, compliant, and well-organized laboratory environment.Follow applicable safety, quality, and training requirements (e.g., GLP, ISO, internal EHS standards).Contribute to continuous improvement of downstream laboratory workflows and experimental practices.Support preparation of bills of materials and logistical needs for BDC projects and customer activities.

Qualifications

Education

B.S. in Chemical Engineering, Biochemistry, Biotechnology, Bioengineering, or related field with 3–5 years of relevant downstream experienceM.S. with 2–3 years of relevant experienceEquivalent combinations of education and experience will be considered

Experience & Skills

Hands-on experience with downstream purification and bioprocessing workflowsFamiliarity with selection, setup, and operation of single-use chromatography columns, flow kits, and UF/DF systems.Experience designing and executing controlled experiments; DoE experience preferredStrong data analysis, documentation, and technical writing skillsProficiency with standard data analysis and reporting tools (e.g., Excel, PowerPoint)

Preferred Attributes

Demonstrated ability to work independently in a fast-paced, matrixed environmentStrong problem-solving skills and attention to detailAbility to translate experimental data into practical, workflow-relevant insightsComfort operating in environments with evolving priorities and requirementsCollaborative, customer-centric mindset

Physical Requirements

Ability to work in a laboratory environment and handle light to moderate lifting (up to 50 lbs)Standing and walking for extended periods during experimental executionManual dexterity to operate laboratory equipment and instrumentation

Why Join the Bioprocess Design Center

The BDC is where Thermo Fisher technologies are stress-tested, validated, and translated into real-world customer solutions. This role offers hands-on exposure to cutting-edge single-use purification systems, ownership of meaningful technical work, and the opportunity to contribute data that directly shapes customer confidence and adoption.

Compensation and Benefits

The salary range estimated for this position based in Massachusetts is $96,000.00–$127,000.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

A choice of national medical and dental plans, and a national vision plan, including health incentive programs

Employee assistance and family support programs, including commuter benefits and tuition reimbursement

At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards