Worcester, MA
6 hours ago
Senior Scientist I, Immunosafety/Immunogenicity

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.


Job Description

The Senior Scientist I will evaluate immunogenic and immunosafety risk potential of candidate therapeutic large molecules in vitro assays. Author preclinical reports to support filing documentation including data aggregation and QC evaluation.

Responsibilities

Execution of in vitro immunogenicity and immunosafety platform for risk assessment including soluble and slide phase cytokine release, T cell proliferation, and cell death bioassays and assessing effector functions of biologic drug candidates.Represent IVIS team on project meetings and designing & coordinating in vitro immunosafety and immunogenicity studies of drug candidates.Author publication, presentations, and/or regulatory documents.
Qualifications

Qualifications

Bachelor’s Degree and typically 10 years of experience OR Master’s Degree and typically 8 years of experience OR PhD and no experience.Degree in Biological Sciences, Cellular Immunology, or related field.Extensive experience with multicolor flow cytometry panel design, BD LSRFortessa instrument operation, BD FACSDive and FlowJo software, and flow cytometry data analysis.Proven track record of successfully handling human samples, isolating cell subsets, and executing bioassays.Experience with report generation for the support of IND documentation a plus.Excellent interpersonal and oral/written communication skills.Results-oriented work ethic and a positive "can-do" attitude with a strong sense of urgency and self-motivated desire to achieve common business goals.Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment.
Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

This job is eligible to participate in our short-term incentive programs. ​

This job is eligible to participate in our long-term incentive programs​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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