Cambridge, MA, United States of America
4 hours ago
Senior Scientist - Cell Biology and Disease Modeling

Job Title: Senior Scientist - Cell Biology and Disease Modeling

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. 

Sanofi Intrépide Research Laboratories is an innovative initiative identifying and advancing breakthrough science, technology, and business opportunities critical to our pipeline strategy. Operating globally with sites in the US and China, we foster an entrepreneurial culture where scientific excellence drives decision-making. Our agile teams work collaboratively to accelerate the delivery of high-impact therapeutics through efficient execution and creative problem-solving.

Join our dynamic US Core Team to develop and implement cellular models that recapitulate human disease biology. This role combines hands-on cell biology expertise with strategic project leadership to accelerate therapeutic discovery through physiologically relevant disease models.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities

Internalize, design and/or establish in vitro and ex vivo cellular models that reflect aspects of human disease pathophysiology, with a focus on immune-mediated diseases, and use to evaluate therapeutic candidate efficacy and mechanism-of-action

Implement advanced cell culture techniques including 3D cultures, co-cultures, and patient-derived systems, with multi-omic, imaging and other read-outs

Establish and validate cellular biomarker assays for translational research applications

Develop and maintain cell biology laboratory capabilities, including equipment procurement and protocol standardization

Collaborate with CROs to implement and transfer cellular model protocols

Interface cross-functionally with research teams to integrate cellular biology data into therapeutic development decisions

About You

Required Qualifications

Bachelor's + 8 years of relevant experience OR

Master's + 5 years of relevant experience OR

Ph.D. + 3 years of relevant experience

Relevant experience in biopharma is preferred

2+ years of biopharma industry experience in cellular model development

Strong track record in establishing disease-relevant cellular systems

Experience with multi-omics, cellular imaging, flow cytometry, and/or high-content analysis

Project management experience including timeline and budget oversight

Preferred Qualifications

Experience with primary human immune and other cells and/or iPSC-derived cellular models

Familiarity with CRISPR gene editing for cellular model development

Experience with microfluidic or organ-on-chip technologies

Experience managing CRO relationships for cellular biology work

Equipment procurement and cell biology lab setup experience

Demonstrated scientific creativity in disease model development

Experience with mechanistic in vivo models of disease

Core Competencies

Deep understanding of cellular biology and human disease mechanisms

Strong analytical and data interpretation skills

Excellence in written and verbal communication of complex biological data

Ability to work effectively in a fast-paced, collaborative environment

Entrepreneurial mindset with calculated risk-taking ability

Why Choose Us?

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Opportunity to shape the future of therapeutic discovery

Highly collaborative, science-driven culture

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$100,500.00 - $145,166.66

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.

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