At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com **Job Function:** Data Analytics & Computational Sciences **Job Sub** **Function:** Bioinformatics **Job Category:** Scientific/Technology **All Job Posting Locations:** Spring House, Pennsylvania, United States of America **Job Description:** Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine Johnson & Johnson Innovative Medicine (JJIM) is currently seeking a **Senior Principal Scientist II, In Silico Biologics,** to join our In Silico Biologics team within the Therapeutics Discovery organization, to be located in Spring House, PA. **Job Description** The Senior Principal Scientist II will work with a core group of scientists and data scientists in executing the strategy for internal and external innovation in evolving areas of antibody design and multifunctional molecule optimization. This will include working with other teams within In Silico Discovery and Biologics Discovery to contribute towards the establishment and execution of strategic initiatives in computational design and AI/ML within this biologics space. Significant time will be spent engaged in collaborations, change management, AI/ML methods development and keeping in the forefront of this evolving area. **Primary Responsibilities** + Partner closely with Biologics Discovery teams to drive drug discovery projects through application of predictive and AI/ML tools for biologics design and optimization. + Mentor junior scientists, fostering their development as expert informatics scientists. + Engage in industry consortia and represent J&J and _In Silico_ Discovery in key initiatives. + Periodically be tasked with evaluating and making recommendations for the acquisition or building of new technologies. This may include performing Due Diligence on potential partnering/M&A opportunities. + Contribute to an inspiring, scientifically rigorous and innovative culture that embraces continuous learning, development and collaboration. + Contribute towards efforts to influence J&J's external environment via scientific publications in peer-reviewed journals and participation in external conferences as needed. **Professional Experience and Qualifications** Required: + A PhD and a minimum of 6 years of experience in drug discovery and development with industry or related leadership experience. + Demonstrated expertise in the field of AI/ML, computation and antibody design & optimization in drug discovery. + Strong understanding of pharmaceutical discovery and optimization processes. + Hands-on experience with large-scale data curation, aggregation, manipulation, integration, mining and analysis, including structured and unstructured data sources. Preferred: + Experience with data visualization tools (e.g. Spotfire, Vortex, Tableau, DataWarrior). + Ability to organize and convey complex data sets in a clear and concise manner to key business partners from diverse backgrounds. + Prior experience leading or participating in collaborations with external academic, biotechnology and contract research organizations. + Strong publication and/or proven track record of supporting discovery of clinical/pre-clinical candidates. + Strong motivation, passion and commitment to science and patients. **Other:** This position will be located at our campus in Spring House, PA (no remote option), and may require up to approximately 5% travel (domestic and international). Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource. The anticipated base pay range for this position is $137,000 to $235,750. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). Employees are eligible for the following time off benefits: Vacation – up to 120 hours per calendar year Sick time - up to 40 hours per calendar year Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market. \#LI-SL \#JNJDataScience \#JNJIMRND-DS \#LI-Hybrid **Required Skills:** **Preferred Skills:** Advanced Analytics, Bioinformatics, Data Privacy Standards, Data Science, Industry Analysis, Interdisciplinary Work, Mentorship, Presentation Design, Productivity Planning, Professional Ethics, Quality Standards, Science, Technology, Engineering, and Math (STEM) Application, Scripting Languages, Statistical Computing, Tactical Planning, Technical Credibility, Technical Writing