Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Position Summary

Reporting to the General Manager, the Senior Manager End-to-End Supply Chain & Operations will lead our efforts to meet quality, cost, and schedule goals. You will be responsible for integrating supply planning, procurement, warehousing, customer service, and manufacturing operations while driving collaboration across functions including R&D, QA/QC, and Engineering. This role is crucial for ensuring reliable product availability, flawless production execution, and cost control in our highly regulated pharmaceutical environment.

Key Responsibilities

End-to-End Supply Chain Ownership

Ensure coordinated planning, sourcing, and inventory strategies meet production and customer demands.Optimize supplier performance, material flow, and warehouse operations.Lead S&OP process execution, driving balance across supply, demand, and capacity.Coordinate customer service to maintain delivery commitments and service levels.

Operations & Manufacturing Execution

Deliver against the weekly and long-term production schedules.Ensure GMP-compliant execution of manufacturing processes.Manage area performance, yield, quality, and efficiency across all shifts.Coordinate operational support functions and training initiatives.

GMP & Regulatory Compliance

Maintain GMP, EH&S, SOP/WI compliance across supply chain and manufacturing.Ensure documentation, validations, and audits meet internal and regulatory requirements.Lead cross-functional CAPA resolution and quality improvements.

People Leadership & Team Development

Lead and develop 10 direct and 150+ indirect reports.Promote a culture of ownership, performance, and continuous improvement.Conduct regular team reviews, goal setting, and succession planning.Champion cross-departmental collaboration to meet site objectives.

Qualifications & Experience

HBO/WO degree in Engineering, Operations, Supply Chain, or Industrial Pharmacy.10+ years in pharmaceutical or food industry operations; 5+ years in senior leadership roles.Strong understanding of GMP, FDA/EU regulations, validation, and quality systems.Proven application of 5S, Lean Manufacturing, Six Sigma tools.Proficient in Dutch and English; German is a plus.Skilled in MS Office, ERP/MES systems, S&OP tools.

Working Conditions

Mix of office, cleanroom, and manufacturing floor presence.Must meet physical requirements including standing, walking, and extended screen time.Domestic and international travel required (up to 10%).Availability for global calls and after-hours meetings as needed.

This is an outstanding opportunity to lead a world-class team and make a significant impact on our operations! Join us at Thermo Fisher Scientific Inc., where your expertise will drive our success.