_Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail._ _This job offer is accessible to all, regardless of gender._ **Job title:** _Senior Lead Clinical Modeler_ + _Location: Marcy l’Etoile_ + _Home office possible in respect with Sanofi global policy. Occasional travel required_ + _Job type: Permanent, Full time_ **_About the job_** The Global Biostatistical Sciences department at Sanofi Vaccines is seeking to hire a highly talented mathematical, statistical and computational modeling scientist to support its Vaccines R&D portfolio. The Global Biostatistical Sciences group is part of the Vaccines R&D organization. Modeling & simulation brings unique opportunities to inform decision making and streamline the various steps of vaccines discovery and development. Are you ready to shape the future of vaccines development? Sanofi is committed speeding up vaccines discovery and development to continuously improve public health and patients’ life. Your talent could be of deep value in helping our project teams accelerate progress through modelling. Join our team as Senior Lead Clinical Modeler, and you’ll actively contribute shaping the future of our vaccines portfolio. **About Sanofi:** We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. **_Main responsibilities:_** + Develop complex quantitative vaccine models (e.g.: virtual individuals immune response in different scenarios, correlate of protections, disease epidemiology, etc.) in close collaboration with multidisciplinary teams to inform and optimize vaccine development + Develop and run in-silico clinical trials in virtual individuals to de-risk, optimize, and accelerate vaccines development + Predict the future through simulations – e.g., Lead the use of models to predict the future trajectory of disease during vaccine trials, including the location, number of cases, peak infections, and duration of transmission and infection in the populations to be studied + Lead the continuous update and refinement of models based on new data and insights from research and real-world results + Assessment and prioritization of modeling strategic contribution to ensure quality and timely impact of modeling and simulation work packages + Clear communication of modeling results (e.g., Prepare reports and presentations to communicate model findings to stakeholders, including decision makers.) + Bring the implementation of scientific and technological innovations in the area of disease and vaccines impact modeling **_About you_** **Education:** + _Ph.D. degree in a quantitative scientific field such as epidemiology, biostatistics, immunology, computational systems biology, or applied mathematics_ **Experience:** + 7+ years experience in pharmaceutical clinical research with at least 3 years modelling experience **Soft and technical skills:** + Mathematical and Statistical Modeling: Demonstrated evidence of comprehensive understanding of mathematical modeling techniques, SEIR models, differential equations, compartmental models, and statistical analysis, ideally evidenced by relevant publications + Epidemiology: Established knowledge of infectious disease epidemiology, including disease transmission, natural history, and control measures. Ability to analyze longitudinal epidemiological data, estimate model parameters, and interpret model outputs + Computer Programming: Demonstrated proficiency in programming languages (e.g., Python, R) for implementing models and in AI/ML + Demonstrate project management skills, customer orientation and influencing skills + Build and maintain effective strategic working relationships with internal and external partners to meet business needs + Identify, develop and implement novel methodologies and invest in expanding expertise across clinical, regulatory, and commercial domains + Demonstrate ability to stay current with the latest research and adapt to new technologies and methodologies + Ability to work independently and collaborate effectively in interdisciplinary teams + Communication: Ability to effectively communicate model results and recommendations to statistical, clinical, and senior management colleagues **_Why choose us?_** + Bring the miracles of science to life alongside a supportive, future-focused team + Collaborate within multidisciplinary teams, leverage cutting-edge technologies, bring innovative modelling solutions to shape the future of vaccines development + Benefit from a well-thought-out benefits package that rewards your contribution and commitment + Pursue your career at an attractive location and experience our modern working environment and benefit from hybrid, flexible working time models **Pursue** **_Progress_** **.** **Discover** **_Extraordinary_** **.** Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue _Progress_ and Discover _Extraordinary_ – together. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law. \#LI-FRA \#LI-Hybrid **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/) Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)