Job Title: Senior Associate Scientist, Ocular In Vivo Translational Sciences

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. 

We are seeking a talented Senior Associate Scientist to join our innovative Ophthalmology Research team at Sanofi.

In this role, you will execute in vivo ocular studies, perform specialized molecular and histological analyses, and contribute to the development of innovative therapies for vision-threatening diseases. As part of our cutting-edge research efforts, you will work on preclinical studies that drive the development of novel ocular therapies from early discovery through IND-enabling stages. This position offers hands-on experience with state-of-the-art techniques in ocular research, with direct impact in ophthalmology drug development.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities

Execute in vivo ocular studies in rodent models, including performing various ocular dosing procedures (intravitreal, intracameral, suprachoroidal, subretinal, topical, systemic)

Conduct molecular analyses including digital PCR, ELISA, and Western blotting on ocular tissues and fluids

Process ocular tissues and perform sophisticated histological techniques on sections and flat mounts, including immunohistochemistry with ocular markers

Operate and maintain automated platforms for molecular and histological assays, ensuring quality control and reproducibility

Perform ocular imaging techniques (OCT, fundus photography, ERG, IOP, OKR) to monitor disease progression and treatment effects

Analyze experimental data, interpret results, and prepare technical reports for team review

Maintain detailed experimental records and contribute to documentation for regulatory submissions

Present findings at team meetings and contribute to scientific discussions

Collaborate with cross-functional teams to advance ophthalmology research programs

About You

Earned Bachelor’s degree and 4+ years of relevant experience in an academic or biopharmaceutical setting OR Master’s Degree +1 year of relevant experience in an academic or biopharmaceutical setting.

Demonstrated experience with molecular biology techniques (dPCR, ELISA, Western blotting) and histological methods

Experience working with laboratory animals (rodents), animal handling, colony maintenance, dosing via different RoA, tissue collections.

Ability to independently execute complex protocols with precision and troubleshoot technical issues

Strong data analysis and visualization skills using relevant software (Excel, GraphPad, ImageJ)

Excellent documentation practices and attention to detail

Strong written and verbal communication skills with ability to present technical information clearly

Demonstrated ability to work both independently and collaboratively in a fast-paced research environment

Preferred Qualifications

Basic understanding of ocular anatomy, physiology, and pathology

Experience working with rodent ocular in vivo models

Experience in ocular drug delivery in rodents and collection of ocular tissues via dissection.

Experience in the assessment of ocular phenotypes ERG, OCT, OKR, IOP, fundus imaging

Experience in immunohistochemistry, and basic imaging techniques

Skills and competencies

Ability to work in a highly collaborative and matrixed environment

Ability to learn new techniques, multi-task and adapt to rapidly changing priorities and deadlines

Excellent written and oral communication skills, with the ability to communicate effectively in a multidisciplinary team

Why Choose Us

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.