_Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail._ _This job offer is accessible to all, regardless of gender._ **Job title :** _Scientist USP_ **_About the job_** As Upstream Process Development Scientist within our CMC Development team, you'll execute experiments and contribute technical expertise to process optimization and scale CHO cell culture platforms. Ready to get started? Join the engine of Sanofi's where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs thatd turn the impossible into possible for millions. Our Drug Substance Process Development & Manufacturing team works at the forefront of biopharmaceutical innovation, transforming early-stage candidates into life-changing treatments. **About Sanofi:** We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system –d innovative pipeline – enables us to in and vaccines that treat and protect millions of people around the world. Together, we chase the mir science to improve people's lives. **Main responsibilities:** + Execute upstream process development activities for early-stage clinical candidates, supporting cell culture process characterization and optimization for clinical manufacturing readiness + Perform experiments using lab-scale bioreactors (15mL to 5L) and advanced platforms including Ambr250 systems, working with multiple culture modes (fed-batch, perfusion, intensifie Conduct cell line evaluation studies, media optimization experiments, and process parameter characterization in sterile working environments + Operate and maintain ATF (Alternating culture applications and contribute to process automation initiatives + Analyze experimental data using statistical and visualization software (JMP or equivalent) and contribute to technical discussions for process development + Collaborate cross-functionally with analytical development, downstream processing, manufacturing, and regulatory teams to ensure project milestones are met + Prepare technical documentation, contribute to development reports, and support technology transfer activities to clinical manufacturing sites **_About you_** + Master's degree in biotechnology, Biochemical Engineering, Cell Biology, or related scientific discipline, OR Bachelor's degree with 2+ years of relevant industrial experience + Hands-on experience with CHO cell culture techniques and lab-scale operations in sterile environments + Proficiency with data analysis and statistical software (JMP or equivalent), with ability to analyze data and draw scientific conclusions + Strong communication skills in English, with ability to present technical information effectively both verbally and in writing + Scientific rigor with attention to detail, analytical thinking, and comfort working in cross-functional team environments + Adaptability and curiosity to learn new techniques in a fast-paced, dynamic environment **Preferred qualifications** : Experience with benchtop bioreactor operations (Ambr250 systems), perfusion and intensified culture processes, ATF technology, automated culture systems, experimental design principles (DOE), and early-stage biopharmaceutical development. **_Why choose us?_** + Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs + Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science + Help improve the lives of millions of people globally by making drug development quicker and more effective + Enjoy opportunities to collaborate beyond your area of expertise, working with diverse teams across science, clinical, and digital fields to spark new ideas and drive breakthroughs + Accelerate your professional development with structured career paths designed for both scientific and leadership advancement, including bold moves that stretch your potential and short-term gigs that build your scientific expertise + Work with state-of-the-art automated and high-throughput culture systems in a laboratory-based environment focused on innovation + Achieve genuine work-life balance in a supportive R&D environment with outstanding benefits, including flexible working options, comprehensive healthcare, and well-being programs designed to help you thrive **Pursue** **_Progress_** **.** **Discover** **_Extraordinary_** **.** Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what's never-been-done-before. You'll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people's lives? Let's Pursue _Progress_ and Discover _Extraordinary_ – together. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law. **\#LI-FRA** **\#LI-Onsite** **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/) Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)