Job Title: Scientist IV Location: Ridgefield, CT Type: Contract Overview Global Pharma company looking to hire and experienced Scientist to join their team. Must bring either a PhD or MS Degree with 6+ years of experience in molecular or cell biology, with 2 years of CRISPR experience. Responsibilities + Design, develop, and execute functional genomics assays, including CRISPR-based editing (e.g., RNP delivery, Perturb-seq), single-cell sequencing, spatial transcriptomics, and CITE-seq. + Provide technical guidance and training to research scientists on FGSL technologies and techniques, including assay execution, troubleshooting, and resolution of technical issues; + Documents and maintains detailed laboratory records in accordance with policies; + Operates and maintains lab equipment in collaboration with other lab members; + Assists acquisition of necessary supplies and equipment; + Defines and performs appropriate QC measures; + Follows relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field; + Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation; + Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports + Automate processing and results reporting and delivery; + Reports and treats data with a high level of integrity and ethics. Requirements + Ph.D. or Master’s degree from an accredited institution with 6+ years of experience in molecular, cell biology, or related scientific discipline. + CRISPR assays - Must have personally designed guides, performed transfections/infections, selected edited cells, and validated knockouts/knockins + Next-generation sequencing (NGS) - Hands-on library preparation experience (not just data analysis) + Single cell technologies - Personal experience with sample prep, library generation, and quality control + Standard molecular biology techniques - qPCR, Western blot, cloning, gel electrophoresis + Cell culture - Proficient in maintaining multiple cell lines, transfections, and sterile technique + Experience in automation is a plus; + Able to perform variety of FGS experimental techniques at the same time; + Ability to troubleshoot FGS experiments both individually and as part of a team. Benefits System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan. Ref: #558-Scientific System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.