Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Laboratory Setting

Job Description

We are seeking a Scientist III with expertise in chemical analysis and molecular biology. The ideal candidate will apply knowledge of qPCR reagent chemistry and advanced analytical methods (HPLC, HPIC, LC/MS) to drive innovation and ensure high-quality reagent performance. This role integrates molecular biology assay development with analytical method design.

Key Responsibilities

Analytical Method Development: Develop, optimize, and validate analytical methods using LC/MS, HPLC, and HPIC for the characterization of nucleic acids, enzymes, buffers, and excipients.

Assay and Reagent Development: Compose and complete qPCR experiments to support reagent formulation, optimization, and performance validation.

Data Analysis and Experimental Development: Apply JMP or equivalent statistical software to build and analyze DOE (Design of Experiments), perform guard-banding, stability, and gauge R&R studies.

Product Characterization and Stability: Perform impurity profiling, ion analysis, and stability studies using chromatographic and spectroscopic methods to ensure long-term product reliability.

Cross-functional Teamwork: Partner with R&D, Product Management, Operations, and Quality teams to integrate analytical data with molecular performance insights throughout product development and manufacturing transfer.

Troubleshooting and Technical Knowledge: Identify root causes of analytical or molecular workflow issues, and provide technical mentorship to project teams.

Documentation and Compliance: Prepare technical reports, method SOPs, and validation summaries consistent with ISO, GMP, and internal quality standards.

Innovation and Continuous Improvement: Contribute to technology evaluations, process improvement initiatives, and intellectual property development related to assay and analytical chemistry.

Keys to Success:

Education

M.S or Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or Bioengineering.

Experience:

3+ years of relevant proven experience in molecular reagent or development of analytical techniques.

Proven hands-on experience with liquid chromatography-mass spectrometry, high-performance liquid chromatography, and fast-paced ion chromatography systems, including method development, validation, and troubleshooting.

Experience performing stability, guard-banding, and robustness studies using statistical and analytical tools.

Knowledge, Skills, and Abilities:

Strong understanding of nucleic acid and protein chemistry, enzyme kinetics, and qPCR reagent formulation.

Familiarity with regulated laboratory environments (ISO, GMP) and method validation guidelines (ICH, FDA, EMA).

Deep understanding of analytical and chromatographic techniques, including ion-exchange, reverse-phase, and ion chromatography principles.

Proficiency in qPCR assay chemistry, data analysis, and statistical build (DOE, regression, multivariate analysis).

Strong analytical problem-solving and data interpretation skills, with the ability to integrate results across platforms.

Effective communicator capable of presenting complex analytical results clearly to cross-functional collaborators.

Good knowledge of English (written and oral) (level B2 - C1).

Diligent, organized, and able to manage multiple projects in parallel.

We Offer:

An innovative environment within a rapidly growing international company.

A hard-working, supportive team and leadership committed to your professional development.

The opportunity to be part of a dynamic organization and work alongside experienced professionals.

A competitive salary range of €2891–€4335 gross, depending on experience and competencies.

At Thermo Fisher Scientific, each one of our 120,000 extraordinary colleagues has a unique story to tell.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate based on race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Compensation

The monthly salary range estimated for this position based in Lithuania is €2 891,67–€4 335,42.