**Job Title:** Scientist – Rare Metabolic and Neurological Diseases **Location** : Cambridge, MA **About the Job** Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. We are seeking a highly motivated and skilled Scientist with deep expertise in rare metabolic, and neurological diseases. The ideal candidate will bring robust hands-on experience in _in vitro_ and _in vivo_ CNS disease modeling, combined with a strong foundation in disease biology and pathophysiology. In this role, you will lead efforts to discover and validate novel therapeutic targets and strategies, leveraging both experimental and analytical approaches. You will collaborate closely with cross-functional teams to translate biological insights into therapeutic programs, contributing to the strategic expansion of our portfolio. **About Sanofi:** We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. **Main Responsibilities** + Support pipeline programs and new program initiation by applying expertise in disease mechanisms, translational biology, and model development + Design and conduct mechanism-of-action and proof-of-concept studies using cellular and animal models of disease + Contribute to interdisciplinary research programs across internal teams and external partnerships, with opportunities to grow into project leadership + Prepare high-quality analyses, documentation, and presentations to support project milestones, publications, patent filings, and regulatory submissions (IND/CTA) + Present findings and progress in internal meetings and external scientific venues **About You** **Core competencies** + Understanding of disease biology in metabolic, mitochondrial, and neurodevelopmental disorders + Experience designing and interpreting functional assays, molecular profiling, and pathway analyses to elucidate disease mechanisms + Demonstrated ability to produce high-quality scientific documentation, including experimental protocols, SOPs, technical reports, and presentations + Proven track record of meaningful contributions to research programs, evidenced by scientific publications and/or presentations **Preferred Technical Skills** + Hands-on experience with disease-relevant _in vitro_ and _in vivo_ models, including cellular, iPSC-derived, or transgenic animal systems + Proficiency with iPSC-derived CNS mono- and co-cultures + Experience performing _in vivo_ studies in rodent models, including dosing (IV, IP, PO), behavioral paradigms, stereotaxic surgeries, CSF extraction, and dissections. + Familiarity with target discovery, preclinical validation, and early drug development workflows **Skills and Competencies** + PhD in a scientific field OR Master’s Degree plus minimum 3 yearsrelevant experience in an academic or biopharmaceutical setting OR Bachelor’s degree plus minimum 6 years of relevant experience in a similar setting + A degree in Neuroscience or a Cell Biology degree with a neuro science focus is preferred + Ability to work independently and collaboratively within cross-functional, matrixed teams + Highly adaptable, with strong multitasking skills and ability to manage shifting priorities and timelines + Strong analytical and problem-solving skills with sound scientific judgment + Clear written and verbal communication skills, able to convey complex concepts to diverse audiences + Interpersonal strengths that foster effective collaboration and productive working relationships + Outstanding organizational skills, attention to detail, and commitment to scientific rigor **Why Choose Us** + Bring the miracles of science to life alongside a supportive, future-focused team. + Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. + Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. + Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. \#GD-SA \#LI-SA \#LI-Onsite \#vhd **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! _US and Puerto Rico Residents Only_ Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. _North America Applicants Only_ The salary range for this position is: $84,000.00 - $121,333.33 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK (https://benefits.sanofiusallwell.com/fleet/public/index/ba511bf8-5c32-4828-9861-ab985fffab90/?cid=sanofi) . Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/) Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)