**Why Mayo Clinic** Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans (https://jobs.mayoclinic.org/benefits/) – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. **Benefits Highlights** + Medical: Multiple plan options. + Dental: Delta Dental or reimbursement account for flexible coverage. + Vision: Affordable plan with national network. + Pre-Tax Savings: HSA and FSAs for eligible expenses. + Retirement: Competitive retirement package to secure your future. **Responsibilities** We are seeking a highly motivated and detail-oriented Research Technologist to join our translational neuro-oncology research team. Our lab focuses on glioblastoma, meningiomas, and peripheral nerve sheath tumors, with a strong emphasis on tumor microenvironment biology, spatial and single-cell transcriptomics, and molecular biomarker discovery through epigenetic modifications. The successful candidate will support ongoing projects by performing established and emerging laboratory techniques, including but not limited to: + Methylated DNA immunoprecipitation from FFPE and frozen tumor tissues, CSF and plasma + Molecular biology assays (PCR, RNA/DNA extraction, qPCR, bisulfite conversion) + H&E staining, immunohistochemistry and immunofluorescence staining on FFPE and frozen tissues + Fluorescence and brightfield microscopy, image acquisition, and analysis + Sample preparation for spatial transcriptomics, single-cell analysis, and next-generation sequencing + Data entry, preliminary statistical analysis, and assistance with manuscript and figure preparation + Organization of lab inventory, reagents, and general lab maintenance The Research Technologist will present data in lab meetings and collaborate closely with senior lab members and trainees. The candidate will be expected to work independently on routine procedures and receive mentorship for more complex tasks. Opportunities for authorship on publications are available based on contributions. **Qualifications** **Qualifications** + Requires bachelor's degree in biology, chemistry, other relevant science, or an associates degree with 6 years of relevant laboratory experience. Bachelor’s degree in biology, biomedical sciences, or a related field is preferred. (Master’s degree or relevant research experience preferred) + Strong preference will be given to those who have a minimum of 3 year of hands-on wet lab experience (academic or industry); associate degree with extensive relevant lab experience will also be considered + Proficiency in molecular biology techniques PCR and qPCR preferred + Familiarity with immunostaining, microscopy, and basic data analysis (GraphPad, ImageJ, Excel/R) preferred + Excellent organizational skills, attention to detail, and ability to work both independently and collaboratively + Strong communication and documentation skills Experience with DNA methylation, digital pathology, or prior exposure to spatial transcriptomics is an asset but not required. Training will be provided. **Exemption Status** Nonexempt **Compensation Detail** Education, experience and tenure may be considered along with internal equity when job offers are extended.; $27.44-41.16/ hour **Benefits Eligible** Yes **Schedule** Full Time **Hours/Pay Period** 80 **Schedule Details** M-F days **Weekend Schedule** as needed **International Assignment** No **Site Description** Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. (https://jobs.mayoclinic.org/alllocations) **Equal Opportunity** All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" (https://www.eeoc.gov/poster) . Mayo Clinic participates in E-Verify (https://www.e-verify.gov/sites/default/files/everify/posters/EVerifyParticipationPoster.pdf) and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization. **Recruiter** Jill Squier **Equal opportunity** As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.