**Why Mayo Clinic** Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans (https://jobs.mayoclinic.org/benefits/) – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. **Benefits Highlights** + Medical: Multiple plan options. + Dental: Delta Dental or reimbursement account for flexible coverage. + Vision: Affordable plan with national network. + Pre-Tax Savings: HSA and FSAs for eligible expenses. + Retirement: Competitive retirement package to secure your future. **Responsibilities** The Mayo Clinic Division of General Internal Medicine is seeking a highly motivated Postdoctoral Fellow to partner directly with the physician leader of our Longevity Research Program. The fellow will oversee ongoing studies and catalyze new, high-impact research focused on disease prevention, metabolic health, and biological aging within the Division of General Internal Medicine. This role is ideal for a scientist-physician or PhD-trained researcher who thrives in translational research, cross-disciplinary collaboration, and rigorous methodology **About the Program** The Longevity Research Program within General Internal Medicine integrates preventive imaging, metabolic phenotyping, aging biomarkers, and genomics to develop actionable, patient-centered models of healthspan extension. We emphasize rigorous methods, data-driven decision-making, and equitable implementation in clinical practice. **Key Responsibilities** + Research Leadership & Oversight + Lead day-to-day execution of active projects, including protocol adherence, recruitment, data collection, analysis, and dissemination. + Coordinate multi-disciplinary teams (clinical investigators, research coordinators, statisticians, data engineers) to achieve milestones on time and on budget. + Study Design & Innovation + Develop new research proposals aligned with program priorities in longevity science; write protocols, IRB submissions, and grant applications. + Apply cutting-edge methods (e.g., machine learning, multi-omics integration) to address clinically meaningful questions. + Data Management & Analysis + Build and maintain high-quality datasets; ensure data integrity, reproducibility, and compliance with institutional and federal regulations. + Collaborate closely with biostatistics and informatics partners. + Scholarly Output + Lead and co-author manuscripts in biomedical journals. + Present findings at national/international meetings. + Contribute to white papers, clinical practice guidance, and knowledge translation. + Regulatory & Compliance + Prepare and manage IRB submissions, amendments, and continuing reviews. + Uphold Good Clinical Practice (GCP), HIPAA, and institutional policies. + Mentorship & Team Culture + Mentor junior trainees (students, residents, research coordinators) in methods and rigor. + Foster an inclusive, collaborative environment. A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Upon background check and CCATS Executive Committee approval, Research Fellow may have patient/research subject contact directly relating to and incidental to the original research program. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic. **Qualifications** + PhD in Epidemiology, Genomics/Computational Biology, Nutrition/Metabolism, Biostatistics, Biochemistry, Physiology, or related field. + Knowledge of research methods, including study design, protocol writing, IRB processes, and patient consent. + Demonstrated experience in clinical/translational research with strong methodological grounding. + Proficiency in statistical programming (e.g., R, Python, SAS) and data management. + Record of peer-reviewed publications commensurate with training stage. + Excellent written and verbal communication skills; proven ability to work in multi-disciplinary teams. + Able to learn new and use new computer programs **Preferred Qualifications** + Experience with imaging research (MRI), advanced biochemical analyses (NMR), aging biomarkers (epigenetic clocks), and/or genomics (PRS). + Familiarity with machine learning and risk prediction modeling. + Prior success with grant writing (e.g., NIH F/K series, foundation awards). + Working knowledge of REDCap and electronic health records (EHR) for cohort development. **Exemption Status** Exempt **Compensation Detail** 68,564.00 - $80,210.00 / year; Education, experience and tenure may be considered along with internal equity when job offers are extended. **Benefits Eligible** Yes **Schedule** Full Time **Hours/Pay Period** 80 **Schedule Details** Varies **Weekend Schedule** Varies **International Assignment** No **Site Description** Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. (https://jobs.mayoclinic.org/alllocations) **Equal Opportunity** All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" (https://www.eeoc.gov/poster) . Mayo Clinic participates in E-Verify (https://www.e-verify.gov/sites/default/files/everify/posters/EVerifyParticipationPoster.pdf) and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization. **Recruiter** Amy Hoffman **Equal opportunity** As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.