Cambridge, Massachusetts
14 days ago
Process Chemist

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Our client is seeking an organic chemist to join their Process Chemistry group. This contract position resides within the Pharmaceutical Sciences organization. The candidate will work full-time onsite and execute laboratory activities related to the development of robust drug substance manufacturing processes across various phases of drug substance development. The ideal candidate will conduct multi-step organic synthesis, route scouting and optimization, purification and characterization of intermediates and final compounds to support drug substance scale-up activities.

An ideal candidate will have a strong foundation in modern synthetic organic chemistry and analytical techniques such as NMR, LCMS, UPLC/HPLC (Empower proficiency) and an understanding of early drug development processes and experiments. Experience in small-molecule process development and scale up is highly desired, however not required.

Responsibilities

Participate in the design, planning and execution of multi-step synthesis, process research and development as a cross-functional team member.Collaborate with cross-functional teams to ensure successful project outcomes.Implement process enhancements, scientific approaches and technical improvements to deliver robust chemical processes.Document and report experimental results and findings.Draft and review technical documents (development reports, patent applications, tech transfer documents etc.) Maintain an accurate, timely and compliant laboratory notebook.Maintain laboratory equipment and ensure compliance with safety regulations.

Requirements

An ideal candidate would have a B.S. or M.S. in Chemistry, or a related field with 3+ years of experience in pharmaceutical research or laboratory setting or, Ph.D. with 0-3+ years of experience.Strong knowledge of organic chemistry.Experience with early phase route development and process optimization Proficiency in using analytical instruments (HPLC/UPLC, NMR, LCMS) and software.Strong analytical and problem-solving skills.Strong written and verbal communication skills.Ability to work independently and as part of a team.Strong organizational and time management skills.Ability to effectively prioritize and manage multiple tasks and compounds Ability to adapt to change and to work optimally within a variety of situations Ability to build productive working relationships across functions and highly diverse groups of individuals Self-motivated and willing to "learn on the job" and ask for assistance when needed Ability to make a significant impact in a results-driven environment where accountability is key.A team player, who listens effectively and invites response and discussion A collaborator who communicates in an open, transparent, complete, timely and consistent manner P1427867BOSJB_1756308745 To Apply for this Job Click Here

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