As a **Principal Biostatistician** , you will play a critical role in shaping real-world evidence (RWE) strategies across the organization. You will lead statistical design and analysis for our clinical registry project—a cornerstone initiative for understanding long-term clinical outcomes. This role partners closely with surgeons, clinical experts, and cross-functional teams to generate high-quality evidence, publish impactful research, and present findings at scientific meetings. **What You Will Do** + Lead the statistical analysis and methodological development for the clinical registry project, ensuring robust evidence generation from registry data. + Partner with surgeons and clinical experts to define study questions, interpret results, and co-develop high-impact scientific outputs. + Drive the development and authorship of manuscripts, abstracts, and presentations based on registry analyses for peer-reviewed journals and international conferences. + Provide statistical leadership in study design, analysis planning, and reporting for registry-based studies and other RWE initiatives across the portfolio. + Advise on advanced methods for real-world data, including causal inference, survival and longitudinal modelling, and handling of complex registry datasets. + Ensure compliance with regulatory standards, industry guidelines, and best practices for RWE study conduct. + Represent the organization externally with academic collaborators, professional societies, and regulatory/payer bodies. + Develop statistical analysis plans, coordinate and perform data analysis and validation as necessary, and provide data interpretation. + Stay current with new developments in statistics, SAS programming, and regulatory guidance through literature review, conference attendance, etc. + Perform analyses; inputs to the statistical section of the study report. Provide statistical insight into interpretation and discussion of study results. + Develop and test SAS programs to generate data sets, tables, listings, and graphs. **What You Need** + MS in Statistics, Biostatistics, Epidemiology, or related quantitative discipline with 8+ years of experience **or** PhD with 5+ years of experience. + Expertise in registry-based research and real-world data sources. + Strong proficiency in statistical programming (SAS, R, or Python). + Knowledge of regulatory guidelines (FDA/CFR; ISO14155). + Proven ability to influence study strategy and regulatory/payer discussions. + Excellent scientific writing and presentation skills with a track record of publications. + SAS proficiency including use of a variety of statistical procedures, e.g., nonparametric analysis, linear and non-linear models, categorical data and survival analysis. **Preferred Qualifications:** + Experience supporting publication of analysis results (abstracts, posters, manuscripts). + Advanced knowledge of registry design and analysis. + Ability to explain statistical concepts to non-statisticians and collaborate effectively. + Strong organizational and time management skills. + $138,700.00 - 226,900.00salary plus bonus eligible + benefits. Individual pay is based on skills, experience, and other relevant factors. This role will be posted for a minimum of 3 days. Health benefits include: Medical and prescription drug insurance, dental insurance, vision insurance, critical illness insurance, accident insurance, hospital indemnity insurance, personalized healthcare support, wellbeing program and tobacco cessation program. Financial benefits include: Health Savings Account (HSA), Flexible Spending Accounts (FSAs), 401(k) plan, Employee Stock Purchase Plan (ESPP), basic life and AD&D insurance, and short-term disability insurance. Stryker offers innovative products and services in MedSurg, Neurotechnology, Orthopaedics and Spine that help improve patient and healthcare outcomes. Alongside its customers around the world, Stryker impacts more than 150 million patients annually. Depending on customer requirements employees and new hires in sales and field roles that require access to customer accounts as a function of the job may be required to obtain various vaccinations as an essential function of their role. Stryker Corporation is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, or protected veteran status. Stryker is an EO employer – M/F/Veteran/Disability.