**Job Description** Salary: $74,692 Department: Department of Stem Cell Biology and Regenerative Medicine; Department of Medicine Physical work location: 1468 Madison Ave, Annenberg 25-20, New York 10029, NY Name PI or Supervisor: Tianliang Sun, tianliang.sun@mssm.edu , +1-6465893887 Web link to Lab: http://www.tianliangsunlab.com/ Web link to Department: https://icahn.mssm.edu/about/departments/regenerative-biology Administrative Contact: Chou, Hsin hsin.chou@mssm.edu ; 212-659-9219 **Qualifications** Educational and other Requirements for the position: PhD degree in life science Experience Required: Training in Biomedical Science and hands on experiments in mouse genetics, molecular and cellular biology, and biochemistry. Goals/Outcomes of the Research Project: Discover new mechanism of liver regeneration and diseases. Publish results in top-tier peer review scientific journals. SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 033 - Liver MSH - ISM, Icahn School of Medicine **Responsibilities** Details of Research Project: Dr. Hao Xiang will perform the following research projects under the mentoring of Dr. Tianliang Sun: 1. Mechanism of boosting of liver regeneration to reverse MASH. Combining multiomics data profiling, mouse genetics, histology, intravital imaging and organoid systems, we will systemically analyze the mechanism of inflammation resolution, lipid metabolism and fibrosis regression events upon the deletion of ZNRF3 and RNF43. 2. The plasticity of biliary epithelial cells during ductular reaction. We aim to dissect the cell heterogeneity of biliary epithelial cells during liver injuries and the key signaling pathways that involved in regeneration and pathogenesis via various mouse genetic and injury models and organoid cultures. 3. Principles of liver zonation regulation and how zonation play a role in liver diseases Technical Duties: (include any protocols) Mouse handling and monitoring, organoid culture, multiomicas data analysis, histology and tissue processing, IF staining, image J based cell and tissue quantification, microscope imaging in fixed tissue and in live mouse, buffer preparation and lab maintenance, genotyping PCR, data recording and analysis, presentation in meetings and work in progress. **About Us** **Strength through Unity and Inclusion** The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history. **About the Mount Sinai Health System:** Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally. **Equal Opportunity Employer** The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization. **Compensation Statement** Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.