**Job Description** Details of Research Project: Deep brain stimulation (DBS) is an effective treatment for severe and chronic neuropsychiatric symptoms that are poorly controlled with medication or psychotherapy. Despite individual successes, the precision of targeting and optimizing stimulation parameter selection and long-term management remains a hit-or-miss endeavor. Our group recently developed a connectome-based precise targeting approach for subcallosal cingulate DBS in depression, and it improves response rates from 43% to 80%. However, therapeutic pathways for the anterior limb of the internal capsule (ALIC) DBS in OCD are still unknown. Another important challenge toward precision DBS is the heterogeneity of psychiatric disorders. A growing body of evidence has found the usage of multimodal neuroimaging to identify disease subtypes and predict optimal treatment assignments such as medication or psychotherapy. However, no known biomarkers exist to determine the patient population most likely to benefit from DBS. In this project, we will generate a connectome atlas of ALIC that specifies which white matter pathways to target with DBS to treat OCD effectively. We will map patient-specific tractography activation pathways with ultra-high field 7T DWI data, which will be correlated with clinical improvement. In addition, we will evaluate the multimodal neuroimaging dataset (structural and functional neuroimaging) of depression and OCD to establish patient selection imaging biomarkers for psychiatric DBS treatment. **Qualifications** Educational and other Requirements for the position: Ph.D. or M.D. or M.D./Ph.D. Experience Required: + More than 2 years of experience in multimodal neuroimaging statistical analysis + More than 2 years of experience in neuroimaging in deep brain stimulation Goals/Outcomes of the Research Project: + Identify key therapeutic pathways and build a new probabilistic stimulation atlas for ALIC DBS in OCD. + Develop personalized DBS targeting for ALIC DBS to improve OCD symptoms. + Characterize depression and OCD subtypes using structural and functional neuroimaging to establish patient selection biomarkers for psychiatric DBS. **Responsibilities** Technical Duties: (include any protocols) + Diffusion-weighted imaging (DWI) data preprocessing and analysis + Diffusion tractography analysis of various psychiatric disorders, including OCD and Depression. + Resting-state functional data preprocessing and analysis + Statistical analysis on multimodal imaging dataset + Neural computation modeling of Deep brain stimulation + Anatomical data preprocessing and analysis **About Us** **Strength through Unity and Inclusion** The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history. **About the Mount Sinai Health System:** Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally. **Equal Opportunity Employer** The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization. **Compensation Statement** Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.