Looking to launch your career at the cutting edge of healthcare? Join Sanofi for a chance to develop with mentoring and guidance from inspirational leaders while helping to make an impact on the lives of countless people worldwide. **About us** You will **write your Master-Thesis** in our team and be advised by biostatisticians from Sanofi’s Evidence Generation and Decision Science (EGDS) unit who are specialized in Immunology & Inflammation. You will have access to expertise in Clinical Statistics, Statistical Modelling and Real-World Evidence. **Topic:** + Context: Treatment effects in clinical studies are affected by natural variability in the population, adding to uncertainty in estimation. Classic analysis approaches often only adjust for a small number of patient characteristics to account for this. + Solution: PROCOVA is an innovative analysis approach using patient-based prognostic scores derived from multiple patient characteristics. Adjustment by these scores allows for more precise estimation and increase in power, potentially leading to smaller sample sizes **Your task** + Develop and implement a PROCOVA score for Hidradenitis Suppurativa + Prepare extensive datasets available from Placebo patients collected in multiple clinical studies (i.e. selection of relevant studies, dataset creation following programming standards) + Systematic analysis and documentation of patient characteristics and data limitations + Implement various prognostic models using different methodological approaches + Perform evaluation and comparison of models using real clinical data + Document and present results and recommend actions for future PROCOVA modelling **Requirements & Qualification** + You are in your studies of Statistics, Data Science, Mathematics (or similar) and you have to write your masters thesis (please let us know the processing time for the thesis according to your examination regulations) + Good programming knowledge in R is a requirement, SAS is an advantage. Experience with GitHub is desirable + A plus: Experience in working with medical data and Machine Learning + Keen interest in pharmaceutical processes + Ability to work independently and as a team player + Highly motivated analytical problem solver with a keen eye for detail and a strong self-motivation + Excellent communication skills + Fluent spoken and written English (required) and German ​ **Why choose us?** + Bring the **miracles of science** to life alongside a supportive, future-focused team + An **international work environment** , in which you can develop your talent and realize ideas and innovations within a competent team + Discover endless opportunities **to grow your talent** and drive your career, whether it’s through a promotion or lateral move, at home or internationally + Benefit from our **mobile office policy** working up to 60% hybrid, depending on the area of assignment, within Germany + Play an instrumental part in **creating best practice** + Start your career at an **attractive location** in the center of Germany and experience our modern working environment \#InvestInEarlyTalent (https://www.linkedin.com/feed/hashtag/?keywords=investinearlytalent&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7247242020925181952) \#Sanofi Hashtag (https://www.linkedin.com/feed/hashtag/?keywords=pursueprogress&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7247242020925181952) \#Pursueprogress Hashtag (https://www.linkedin.com/feed/hashtag/?keywords=discoverextraordinary&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7247242020925181952) \#DiscoverExtraordinary \#Sanoficareers (https://www.linkedin.com/feed/hashtag/?keywords=sanoficareers&highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7247242020925181952) **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/) Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)