By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice (https://jobs.takeda.com/privacynotice) and Terms of Use (https://www.takeda.com/terms-and-conditions/) . I further attest that all information I submit in my employment application is true to the best of my knowledge. **Job Description** **Role Purpose** The **Senior Director, Global Medical Lead (GML), PDT+ Pipeline** is the strategic owner of the **global medical strategy** for the **BKV program** and PDT+ pipeline developments (current focus includes, but is not limited to, **BKV / Renal Transplant** ). This is a high-impact, enterprise-facing role spanning **strategy definition, evidence generation leadership, scientific platform oversight, global launch excellence, external influence** , and **matrix leadership** across regions, LOCs, and cross-functional partners. **Key Objectives** + Own and drive the multi-year **global medical strategy** for the BKV program and PDT+ pipeline product/disease area. + Build global medical capacity for the relevant pipeline product/disease area, including **expanded access** strategy support. + Serve as the **global subject-matter expert** within PDT+ and across functions for the pipeline product/disease area. + Lead cross-functional alignment to deliver scientific excellence from early development through launch. **Key Accountabilities** + Lead the development and execution of a **multi-year global medical strategy** for the pipeline product/disease area, including publications strategy, evidence generation, congress strategy, HCP interaction strategy, and the scientific communication platform—aligned with overall strategy and R&D functional strategies (clinical, regulatory, GEO, safety, compliance). + Serve as the **global Medical Affairs leader** for the pipeline product/disease area and represent the asset at the enterprise level, contributing to portfolio strategy and long-range medical planning. + Set medical strategic imperatives and ensure alignment with **Clinical Development, Regulatory, Market Access/HEOR, Commercial** , and regional/LOC medical teams. + Develop and execute the **Global Medical Plan** , including: + Scientific positioning + Scientific communications strategy + Evidence generation strategy + External engagement strategy + Engage early with **Pharmaceutical Sciences** and **Business Development** to identify and evaluate new assets. + Lead and inspire **Medical Strategy Teams** , ensuring strong collaboration with regional and LOC partners (publications, medical communications, medical training, evidence generation). + Provide strategic input to R&D and senior management within the PDT business unit; lead in a matrix across Medical Affairs and at GPT level as appropriate. + Own the medical budget for the product/disease area (approx. **0.1–3.0 Oku Yen** ). Scientific Communications & Positioning + Drive scientific positioning and lead pre-launch and launch scientific communications, including: + Publication strategy + Congress strategy and congress selection + Scientific platform + Medical Core Story External Engagement + Establish strategic partnerships with centers of excellence, key external experts/HCPs, scientific societies, and patient organizations (in collaboration with Patient Advocacy). + Act as Takeda’s senior representative for relevant external audiences. + Partner with Legal, Compliance, and Regulatory to ensure appropriate and ethical external interactions. + Plan, design, and lead global **Advisory Boards** as appropriate, including global speaker strategy. Evidence Generation Leadership + Lead the **Integrated Evidence Strategy** , including: + Phase 3/4 and lifecycle clinical strategy + Real-world evidence planning + Registries and long-term extension programs + HTA/SAP, burden of illness, and comparative analyses + Drive cross-functional evidence prioritization to support label, access, value narrative, and global differentiation. + Ensure global rigor and excellence in data dissemination. + Lead design and execution of Medical Affairs company-sponsored and collaborative studies (Phase IIIb/IV, registries, observational/non-interventional, epidemiology, outcomes surveys) in close collaboration with TAU representatives and Global Clinical Operations. + Monitor progress against the medical plan and adapt initiatives as needed based on disease area requirements. People & Capability Development + Build global medical capabilities (e.g., medical training, analytics maturity, scientific communications excellence). + Foster an enterprise mindset and culture of scientific excellence. **Qualifications** **Required** + Advanced medical or scientific degree ( **MD, PharmD, or PhD** preferred), ideally with clinical experience in **Transplant Medicine, Immunology, or Nephrology** . + Demonstrated experience across the scope of the role through Clinical/R&D/Medical Affairs work, with expertise in **Nephrology, Transplant, and/or Immunology** . + **11+ years** in Medical Affairs and scientific leadership, with a strong track record in strategy development, product development, and launch strategy. + Proven ability to lead cross-functional teams in a **matrix** environment. **Preferred** + Clinical experience in Nephrology and/or Transplantation. + Field-based experience (e.g., Medical Director, Medical Science Liaison) a plus. + Clinical development experience preferred. **Skills & Competencies** + Strong scientific acumen and understanding of clinical medicine + Strategic thinking, proactive mindset, and execution focus + Hands-on leadership, strong collaboration and influence skills + Strong intercultural competence and commitment to global diversity **Locations** Zurich, Switzerland **Worker Type** Employee **Worker Sub-Type** Regular **Time Type** Full time