At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com **Job Function:** Discovery & Pre-Clinical/Clinical Development **Job Sub** **Function:** Clinical Development & Research – MD **Job Category:** Scientific/Technology **All Job Posting Locations:** Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America **Job Description:** Johnson & Johnson, is recruiting for an **Executive Medical Director, Clinical Leader- Neuroscience Early Development & Experimental Medicine** to be located in Raritan, NJ, Titusville, NJ, Cambridge, MA or Spring House, PA. Remote work options may be considered on a case-by-case basis and if approved by the Company. Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Neuroscience team tackles the world’s toughest brain health challenges including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, myasthenia gravis, epilepsy, major depressive disorder, bipolar disorder, schizophrenia, and autism. This patient-focused team helps address some of the most complex diseases of our time. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine The Clinical Leader for Neuroscience Early Development & Experimental Medicine will serve as the clinical lead for multiple early‑stage programs in Alzheimer’s disease, Parkinson’s disease, and related neurodegenerative indications. This role will be accountable for shaping the clinical strategy, designing and overseeing early‑phase clinical studies, and driving programs from first‑in‑human through Proof‑of‑Concept. The role requires deep scientific and clinical expertise in neuroscience, strong leadership in cross‑functional drug development, and the ability to operate in an innovation‑focused environment. The Director/Executive Director will partner closely with discovery, translational science, biomarkers, clinical pharmacology, biostatistics, regulatory, and external academic collaborators to advance transformative therapies for patients. **Duties and responsibilities include, but are not limited to the following:** + Develop and lead clinical development strategies from IND/CTA through Phase I and Phase IIa Proof‑of‑Concept/Proof-of-Mechanism. + Integrate translational hypotheses, biomarker strategies, precision measures (for patient selection, pharmacodynamic measures) and patient‑centric approaches into clinical plans. + Ensure scientific rigor, clinical feasibility, and regulatory alignment in all development strategies. + Lead the design of innovative and lean signal seeking early-phase clinical trials, including adaptive and biomarker‑enriched designs. + Provide clinical oversight for study execution, including safety monitoring, dose selection, protocol amendments, and data interpretation. + Leads cross-functional clinical study teams and work closely with biomarker, PK/PD, biostatistics, and operations teams to ensure high‑quality clinical execution. + Be a core member of the early development compound team for specific assets. Guide decision‑making at project milestones and participate in governance reviews. + Engage with regulatory affairs to inform early interactions with FDA, EMA, and other agencies. + Establish and maintain relationships with global key opinion leaders, academic partners, and clinical investigators. + Represent the company at scientific meetings, advisory boards, and consortiums in neuroscience and neurodegeneration. + Contributes to in-licensing evaluations and due-diligence activities. + Provide scientific and strategic leadership to clinical scientists and clinical development team members. + Mentor or manage junior clinicians or scientists within Early Development and Experimental Medicine. + Promote a culture of scientific excellence, patient focus, and collaborative innovation. **Education Required:** + MD, MD/PhD, or equivalent clinical degree required; board certification in Neurology or Psychiatry strongly preferred. **Requirements:** + Minimum 5 years of clinical research experience in the biopharmaceutical industry, academia, or equivalent setting. + Demonstrated experience leading early‑phase clinical trials; experience in PD, AD is highly desirable. + Proven track record of advancing programs through early development milestones. + Deep understanding of neurodegenerative diseases, including Alzheimer’s and Parkinson’s biology, clinical endpoints, and emerging modalities. + Strong knowledge of translational neuroscience, biomarkers, and experimental medicine approaches. + Experience with innovative trial designs, digital health tools, or fluid/imaging biomarkers is a plus. + Strategic thinker with the ability to influence and drive cross‑functional teams. + Outstanding communication and presentation skills, with the ability to engage senior leadership, and ensures alignment between various teams and stakeholders. + Demonstrated ability to work in an agile, innovation‑driven environment. The anticipated base pay range for this position is $232,000 to $401,350. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis. · + Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. + Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). + This position is eligible to participate in the Company’s long-term incentive program. + Employees are eligible for the following time off benefits: + Vacation – up to 120 hours per calendar year + Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year + Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year + Additional information can be found via the following link: https://www.careers.jnj.com/employee-benefits The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or contact AskGS to be directed to your accommodation resource. \#LI-Hybrid **Required Skills:** **Preferred Skills:** Clinical Research and Regulations, Clinical Trials, Collaborating, Drug Discovery Development, Innovation, Program Management, Regulatory Affairs Management, Research Ethics, Scientific Evaluation, Scientific Research, Strategic Change